VIP
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Vasoactive Intestinal Peptide (VIP) – Neurovascular and Cellular Signaling Research Peptide
Overview:
Vasoactive Intestinal Peptide (VIP) is a 28–amino acid regulatory peptide extensively studied for its roles in vasodilation, neuroprotection, circadian rhythm regulation, and immune modulation. As a member of the secretin/glucagon peptide family, VIP is a cornerstone molecule in cellular signaling, receptor-binding, and neurovascular communication research.
Scientific Background:
VIP interacts with VPAC1 and VPAC2 receptors, activating adenylate cyclase and increasing intracellular cyclic AMP (cAMP) levels—key pathways in smooth muscle relaxation, neuroendocrine signaling, and immune balance. Research has explored its involvement in vascular tone regulation, neural tissue protection, and inflammatory control, offering valuable insights into homeostatic and restorative biological mechanisms.
Due to its multifunctional nature, VIP continues to serve as a model compound in studies of neurovascular function, metabolic signaling, and peptide-mediated cell communication.
Why Researchers Study VIP:
VIP provides a powerful model for exploring neurovascular, metabolic, and immune system cross-talk. Its well-defined receptor activity and broad physiological relevance make it a vital peptide for studying cellular resilience, vascular homeostasis, and neuroimmune signaling in modern peptide research.
? For Laboratory Research Use Only. Not for Human Consumption.
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